AASS

Across TCGA cell cohorts, AASS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,450 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible AASS-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Nuclear export, and Nucleocytoplasmic transport. Each is linked with AASS in more than 12 cancer types. Because this analysis shows association rather than direction, both AASS-to-partner and partner-to-AASS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by AASS-low versus AASS-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AASS→partner) and Y-score (partner→AASS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.061	+1.072	<.001	.001	3	12
BONE	Nuclear export →	+0.096	+1.570	<.001	<.001	3	12
BONE	Nucleocytoplasmic transport →	+0.067	+1.346	.003	.004	2	13
BONE	Microtubule polymerization or depolymerization →	+0.132	+1.564	<.001	<.001	3	11
BONE	Nuclear transport →	+0.067	+1.346	.003	.004	2	12
BONE	RNA localization →	+0.124	+1.354	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,450 associations by consensus.

Positive regulation of organelle assembly by AASS expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →