AADACL2-AS1

Across TCGA patient cohorts, AADACL2-AS1 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AADACL2-AS1-associated genes across cancer lineages are SNORD11B, RNA5SP414, and RNA5SP411. Each is linked with AADACL2-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AADACL2-AS1-to-partner and partner-to-AADACL2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD11B grouped by AADACL2-AS1-low versus AADACL2-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AADACL2-AS1→partner) and Y-score (partner→AADACL2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD11B →	+0.804	+3.061	<.001	.002	3	1
UCEC	RNA5SP414 →	+0.982	+3.577	<.001	<.001	3	1
UCEC	RNA5SP411 →	+1.485	+2.715	<.001	.006	3	1
UCEC	RNA5SP412 →	+1.010	+3.289	<.001	.001	3	1
UCEC	HNRNPCL3 →	+0.052	+2.871	.001	.007	3	1
UCEC	RNVU1-28 →	+0.875	+2.635	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

SNORD11B by AADACL2-AS1 expression — UCEC

Explore this box plot interactively →