AADACL2-AS1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AADACL2-AS1 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AADACL2-AS1-associated genes across cancer lineages are Th2 cells and Endothelial cells. Each is linked with AADACL2-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AADACL2-AS1-to-partner and partner-to-AADACL2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Th2 cells grouped by AADACL2-AS1-low versus AADACL2-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AADACL2-AS1→partner) and Y-score (partner→AADACL2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTh2 cells →+0.379+3.008<.001.01921
UCECEndothelial cells →-0.051-2.957.020.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Th2 cells by AADACL2-AS1 expression — UCEC

Box plot of Th2 cells in AADACL2-AS1-low vs AADACL2-AS1-high samples in UCEC.

Explore this box plot interactively →

Exploration