AADAC

Across TCGA patient cohorts, AADAC RNA expression is significantly associated with the protein abundance of many other proteins, with 7,367 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AADAC-associated proteins across cancer lineages are ALDH1A1, IQGAP2_S16, and SH3BGRL2. Each is linked with AADAC in more than 3 cancer types. Because this analysis shows association rather than direction, both AADAC-to-partner and partner-to-AADAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AADAC versus ALDH1A1 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AADAC→partner) and Y-score (partner→AADAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ALDH1A1 →	+0.743	+1.484	<.001	<.001	3	4
LUAD	IQGAP2_S16 →	+0.717	+1.099	<.001	.001	3	3
BRCA	SH3BGRL2 →	+0.391	+0.592	.001	.002	3	3
LSCC	TACC2_S473 →	+1.173	+1.235	.001	.003	3	3
BRCA	ADD3 →	+0.442	+0.603	<.001	<.001	3	3
LSCC	CELSR1 →	+0.339	+1.523	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,367 associations by consensus.

AADAC vs ALDH1A1 — HNSC

Explore this scatter interactively →