A2ML1-AS2

Across TCGA patient cohorts, A2ML1-AS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,641 significant associations in total. STAD shows the largest number of these associations.

The most reproducible A2ML1-AS2-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, Regulation of protein ubiquitination, and Positive regulation of protein ubiquitination. Each is linked with A2ML1-AS2 in more than 11 cancer types. Because this analysis shows association rather than direction, both A2ML1-AS2-to-partner and partner-to-A2ML1-AS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alternative mRNA splicing, via spliceosome grouped by A2ML1-AS2-low versus A2ML1-AS2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (A2ML1-AS2→partner) and Y-score (partner→A2ML1-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Alternative mRNA splicing, via spliceosome →	+0.075	+0.220	<.001	<.001	3	12
STAD	Regulation of protein ubiquitination →	+0.065	+0.266	<.001	<.001	3	12
STAD	Positive regulation of protein ubiquitination →	+0.059	+0.244	<.001	<.001	3	12
STAD	Regulation of telomere maintenance →	+0.066	+0.235	<.001	<.001	3	12
STAD	Ribosomal large subunit biogenesis →	+0.068	+0.213	<.001	<.001	3	12
STAD	RNA-templated DNA biosynthetic process →	+0.067	+0.219	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,641 associations by consensus.

Alternative mRNA splicing, via spliceosome by A2ML1-AS2 expression — STAD

Explore this box plot interactively →