A2ML1-AS2

Across TCGA pan-cancer cohorts, A2ML1-AS2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of A2ML1-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where A2ML1-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types A2ML1-AS2 is over-expressed in tumor.

LUSC are the cancer types where A2ML1-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in A2ML1-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	+0.050	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

A2ML1-AS2–LUSC

Open the LUSC breakdown →