Positive regulation of metalloendopeptidase activity

associated omics data
GO:1904685Ontology (GO BP)GO biological process · ~4 member genes

Q-omics provides the Positive regulation of metalloendopeptidase activity (GO:1904685) pathway profile, scoring each patient from the combined activity of its roughly 4 member genes. Additionally, pathway RNA activity shows 20,755 significant cross-omics associations, again with the highest sampling consensus in GBM.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns. Pathway-against-pathway and pathway-against-mutation comparisons are not available for ontology entities.

Cross-omics associations

This table shows molecular features associated with Positive regulation of metalloendopeptidase activity pathway activity in patient tissues and cancer cell lines. In patient samples, pathway activity is most strongly linked to RNA and protein features, with the largest associated set in GBM. In cancer cell lines, RNA-expression features and functional dependencies dominate, with the largest set in BLOOD_Leukemia.
Associated data typeStrength (# associated data)Lineage of highest associated data
Protein (mass-spec)
Protein (mass-spec)20,755GBM (7863)view →
RNA4,172GBM (1781)view →
RNA
Protein (mass-spec)14,240GBM (9244)view →
Associated data typeStrength (# associated data)Lineage of highest associated data
shRNA
RNA691BLOOD_Leukemia (160)view →
shRNA499SKIN (91)view →