Carbohydrate derivative transport

Across TCGA cell cohorts, RNA activity of the Carbohydrate derivative transport pathway is significantly associated with the RNA expression of multiple genes, with the UPPER_AERODIGESTIVE_TRACT cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are FARP1, CKMT1B, and RPS27L, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, FARP1 grouped by Carbohydrate derivative transport-low versus -high activity in UPPER_AERODIGESTIVE_TRACT.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	FARP1 →	-2.144	-1.004	<.001	.001	3	5
CNS	CKMT1B →	+1.825	+0.821	<.001	<.001	3	5
OVARY	RPS27L →	-1.312	-1.009	.004	.002	3	5
OVARY	FAM221A →	+2.151	+1.362	<.001	<.001	3	4
CNS	LIMS4 →	-0.935	-0.743	.002	.001	3	4
SOFT_TISSUE	EEF2K →	-0.653	-1.288	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

FARP1 by Carbohydrate derivative transport activity — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →