Walking behavior

Across TCGA cell cohorts, RNA activity of the Walking behavior pathway is significantly associated with the RNA expression of multiple genes, with the STOMACH cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are KIZ, KCTD15, and WNT7B, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, KIZ grouped by Walking behavior-low versus -high activity in STOMACH.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	KIZ →	+1.944	+1.248	.005	.007	3	5
LIVER	KCTD15 →	-1.373	-1.910	.003	<.001	3	4
LIVER	WNT7B →	+2.956	+1.910	<.001	<.001	3	4
SOFT_TISSUE	TIMP1 →	+1.899	+1.108	.004	.008	3	3
SOFT_TISSUE	EXOSC8 →	-0.952	-1.687	.008	.002	3	3
SOFT_TISSUE	UBTD2 →	-0.637	-1.621	.008	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

KIZ by Walking behavior activity — STOMACH

Explore this box plot interactively →