Angiogenesis involved in coronary vascular morphogenesis

Across TCGA patient cohorts, RNA activity of the Angiogenesis involved in coronary vascular morphogenesis pathway is significantly associated with the RNA expression of multiple genes, with the COAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LINC01147, LARP1B, and SYNPO2, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Angiogenesis involved in coronary vascular morphogenesis activity versus LINC01147 in COAD (Pearson r = 0.11).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01147 →	+0.131	+0.092	<.001	.005	3	4
UCEC	LARP1B →	-0.419	-0.559	<.001	.002	3	4
BRCA	SYNPO2 →	+1.301	+0.536	<.001	.004	3	4
CCRCC	COPE →	-0.221	-0.169	.005	.004	3	4
BRCA	FGF2 →	+1.327	+0.479	<.001	.002	3	4
CCRCC	RPL36AP13 →	+0.369	+0.219	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0060978 vs LINC01147 — COAD

Explore this scatter interactively →