Regulation of sensory perception

Across TCGA patient cohorts, RNA activity of the Regulation of sensory perception pathway is significantly associated with the RNA expression of multiple genes, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are BTNL9, GYPE, and GSTM5, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Regulation of sensory perception activity versus BTNL9 in BRCA (Pearson r = 0.18).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BTNL9 →	+0.970	+0.251	<.001	.001	3	4
BRCA	GYPE →	+0.204	+0.208	.006	.009	3	4
PDAC	GSTM5 →	+0.540	+0.253	.002	<.001	3	4
PDAC	ABCA8 →	+1.024	+0.199	<.001	<.001	3	4
PDAC	ZCCHC24 →	+0.683	+0.195	<.001	.001	3	4
PDAC	TMEM100 →	+0.579	+0.170	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0051931 vs BTNL9 — BRCA

Explore this scatter interactively →