Biological process involved in intraspecies interaction between organisms

Across TCGA cell cohorts, RNA activity of the Biological process involved in intraspecies interaction between organisms pathway is significantly associated with the RNA expression of multiple genes, with the STOMACH cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are FOXRED1, TMEM237, and RTF2, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Biological process involved in intraspecies interaction between organisms activity versus FOXRED1 in STOMACH (Pearson r = -0.85).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	FOXRED1 →	-0.902	-2.028	.005	<.001	3	4
BREAST	TMEM237 →	-1.198	-1.122	.008	.009	2	5
BREAST	RTF2 →	-1.058	-1.255	<.001	<.001	3	4
LARGE_INTESTINE	FAM126B →	-0.875	-1.851	<.001	<.001	3	4
SKIN	TRAK2 →	-1.267	-1.131	.001	.005	3	3
SKIN	SH2D3A →	+0.277	+1.222	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0051703 vs FOXRED1 — STOMACH

Explore this scatter interactively →