Vesicle fusion with Golgi apparatus

Across TCGA cell cohorts, RNA activity of the Vesicle fusion with Golgi apparatus pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are SLC29A1, DUT, and SCLY, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Vesicle fusion with Golgi apparatus activity versus SLC29A1 in OVARY (Pearson r = -0.46).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SLC29A1 →	-0.934	-0.868	.007	.001	3	4
OVARY	DUT →	-0.782	-0.746	<.001	.009	2	5
OVARY	SCLY →	-1.218	-0.971	.007	.006	2	5
OVARY	MRPL44 →	-0.616	-0.728	.001	.003	2	5
OVARY	MYG1 →	-0.799	-0.704	<.001	.002	3	4
SOFT_TISSUE	UCK2 →	-0.929	-1.440	.004	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0048280 vs SLC29A1 — OVARY

Explore this scatter interactively →