Monoacylglycerol metabolic process

Across TCGA cell cohorts, RNA activity of the Monoacylglycerol metabolic process pathway is significantly associated with the RNA expression of multiple genes, with the KIDNEY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CLHC1, ABHD2, and TEAD4, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Monoacylglycerol metabolic process activity versus CLHC1 in KIDNEY (Pearson r = 0.73).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	CLHC1 →	+0.763	+1.069	.001	.006	3	5
LUNG_SCLC	ABHD2 →	+1.664	+1.028	.001	.007	3	4
LIVER	TEAD4 →	-1.615	-1.720	.009	<.001	3	4
LIVER	FANK1 →	+2.311	+1.434	<.001	<.001	3	4
SKIN	NUCB2 →	+0.903	+1.278	.006	<.001	2	5
CNS	ABHD12 →	+0.915	+1.239	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0046462 vs CLHC1 — KIDNEY

Explore this scatter interactively →