Eating behavior

Across TCGA patient cohorts, RNA activity of the Eating behavior pathway is significantly associated with the protein abundance of multiple proteins, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are SNX16_S83, SRSF9, and YTHDF3_S385, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Eating behavior activity versus SNX16_S83 in GBM (Pearson r = 0.17).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNX16_S83 →	+0.403	+0.067	.004	.002	3	4
GBM	SRSF9 →	-0.358	-0.055	<.001	.002	3	4
BRCA	YTHDF3_S385 →	-0.837	-0.066	.009	.004	3	4
GBM	CMTR1 →	-0.259	-0.057	.007	.007	3	4
GBM	COX6A1 →	+0.315	+0.051	.003	.001	3	4
GBM	MTA1_S576 →	-0.461	-0.059	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042755 vs SNX16_S83 — GBM

Explore this scatter interactively →