Retinal metabolic process

Across TCGA cell cohorts, RNA activity of the Retinal metabolic process pathway is significantly associated with the RNA expression of multiple genes, with the BONE cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are OXA1L, AGPS, and DCAF11, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Retinal metabolic process activity versus OXA1L in BONE (Pearson r = 0.71).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	OXA1L →	+0.402	+1.556	.007	.006	2	5
URINARY_TRACT	AGPS →	+0.793	+1.471	<.001	<.001	3	4
BREAST	DCAF11 →	+0.692	+0.468	<.001	.006	3	4
BREAST	AZIN2 →	-1.201	-0.534	<.001	.001	3	4
STOMACH	PFKL →	+1.052	+0.381	.009	.004	2	4
KIDNEY	HSPA1B →	+1.182	+1.472	.009	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042574 vs OXA1L — BONE

Explore this scatter interactively →