Olfactory behavior

Across TCGA patient cohorts, RNA activity of the Olfactory behavior pathway is significantly associated with the RNA expression of multiple genes, with the TGCT cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CHD7, GTF3C2, and CCDC120, each associated with the pathway in up to 23 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Olfactory behavior activity versus CHD7 in TGCT (Pearson r = -0.10).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	CHD7 →	+1.269	+0.082	<.001	<.001	3	23
THYM	GTF3C2 →	+0.647	+0.081	<.001	<.001	3	21
THYM	CCDC120 →	+0.733	+0.069	<.001	<.001	3	21
ACC	NFRKB →	+0.606	+0.042	.007	.001	2	22
SARC	NSD2 →	+0.699	+0.035	<.001	<.001	3	20
MESO	ATP6V1B1 →	+2.341	+0.074	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042048 vs CHD7 — TGCT

Explore this scatter interactively →