Chondrocyte proliferation

Across TCGA cell cohorts, RNA activity of the Chondrocyte proliferation pathway is significantly associated with the RNA expression of multiple genes, with the CNS cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CBARP, RANGAP1, and RFC4, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Chondrocyte proliferation activity versus CBARP in CNS (Pearson r = 0.68).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CBARP →	+1.000	+1.156	.001	.004	3	3
CNS	RANGAP1 →	-1.295	-1.792	.006	.005	3	2
CNS	RFC4 →	-0.952	-1.762	.004	.006	3	2
CNS	CAMKV →	+0.392	+1.852	.003	<.001	3	2
CNS	ACOX2 →	+2.920	+1.927	.002	<.001	3	2
CNS	TUBB4B →	-0.622	-1.213	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0035988 vs CBARP — CNS

Explore this scatter interactively →