Animal organ regeneration

Across TCGA patient cohorts, RNA activity of the Animal organ regeneration pathway is significantly associated with the protein abundance of multiple proteins, with the COAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are VTN, KNG1_S332, and CFP, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Animal organ regeneration activity versus VTN in COAD (Pearson r = 0.20).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VTN →	+0.834	+0.164	<.001	.001	2	6
CCRCC	KNG1_S332 →	+0.802	+0.261	<.001	<.001	3	5
UCEC	CFP →	+0.594	+0.192	<.001	<.001	3	5
CCRCC	CPB2 →	+0.604	+0.305	<.001	<.001	3	5
CCRCC	C8B →	+0.516	+0.361	<.001	<.001	3	4
GBM	PEBP1_S54 →	-0.697	-0.186	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0031100 vs VTN — COAD

Explore this scatter interactively →