Glyceraldehyde-3-phosphate metabolic process

Across TCGA patient cohorts, RNA activity of the Glyceraldehyde-3-phosphate metabolic process pathway is significantly associated with the RNA expression of multiple genes, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CENPW, OR7E13P, and RNU6-44P, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Glyceraldehyde-3-phosphate metabolic process activity versus CENPW in BRCA (Pearson r = -0.31).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CENPW →	-1.015	-0.178	<.001	<.001	3	5
UCEC	OR7E13P →	+0.879	+0.081	.001	.001	3	4
UCEC	RNU6-44P →	+0.891	+0.073	.007	.004	3	4
BRCA	HDC →	+1.643	+0.198	<.001	<.001	3	4
BRCA	CCDC150 →	-0.376	-0.103	.003	.001	3	4
BRCA	MTFR2 →	-0.852	-0.127	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0019682 vs CENPW — BRCA

Explore this scatter interactively →