Fucose catabolic process

pathway activity — cross-omics
GO:0019317Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Fucose catabolic process pathway is significantly associated with the RNA expression of multiple genes, with the PDAC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LINC00652, RRN3P2, and MIR4493, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACLINC00652 →-0.144-0.336.004.00533
LSCCRRN3P2 →+0.446+0.116.007.00333
LSCCMIR4493 →+1.406+0.102.004.00233
LUADC3orf86 →-0.728-0.228<.001.00432
COADCASKIN1 →-0.154-0.128.003.00532
COADIGHV1-2 →-2.204-0.133.005.00332
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

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