Viral release from host cell

Across TCGA patient cohorts, RNA activity of the Viral release from host cell pathway is significantly associated with the RNA expression of multiple genes, with the LUAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are STAB1, LRP1, and VENTX, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Viral release from host cell activity versus STAB1 in LUAD (Pearson r = 0.19).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	STAB1 →	+0.608	+0.169	<.001	<.001	3	4
PDAC	LRP1 →	+0.427	+0.110	.001	<.001	3	4
GBM	VENTX →	+1.060	+0.115	<.001	<.001	3	4
PDAC	PDE4A →	+0.256	+0.084	.001	.002	3	4
LUAD	COX7A2 →	-0.330	-0.139	.001	<.001	3	4
LUAD	VASN →	+0.580	+0.170	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0019076 vs STAB1 — LUAD

Explore this scatter interactively →