Hexose phosphate transport

pathway activity — cross-omics
GO:0015712Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Hexose phosphate transport pathway is significantly associated with the RNA expression of multiple genes, with the UCEC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are C1S, RIBC2, and MFFP1, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECC1S →-1.045-0.682.001.00833
COADRIBC2 →-1.076-0.315.001<.00133
HNSCMFFP1 →+1.853+0.117.002.00433
LUADSLC37A4 →+0.612+0.837<.001<.00133
COADRPL21P131 →+0.435+0.341.003<.00133
BRCAESCO2 →-0.713-0.623.001.00833
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration