Q-omics provides the consensus-scored MFFP1 profile across patient tissues and cancer cell-line models. MFFP1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, MFFP1 is differentially expressed in 5, with the highest sampling consensus in COAD. Additionally, MFFP1 RNA expression shows 9,542 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight THCA, COAD, and ESCA as cancer lineages where MFFP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MFFP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MFFP1 survival associations across molecular data types. MFFP1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MFFP1 RNA expression–survival associations across cancer types. High MFFP1 expression shows unfavorable associations in THCA, KIRC, DLBC, LGG and THYM, but favorable associations in LUAD. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for MFFP1 RNA expression.
This table summarizes MFFP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MFFP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MFFP1 shows lower tumor expression in KIRP, KICH and BRCA and higher tumor expression in COAD, KICH and HNSC. The COAD box plot shows higher MFFP1 RNA expression in tumor versus normal tissue (log2 FC = +0.087, t-test p = .009).
This table shows molecular features associated with MFFP1 in patient tissues and cancer cell lines. In patient samples, MFFP1 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
