Detection of visible light

Across TCGA cell cohorts, RNA activity of the Detection of visible light pathway is significantly associated with the RNA expression of multiple genes, with the KIDNEY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are NMRK1, MMAB, and TBC1D17, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Detection of visible light activity versus NMRK1 in KIDNEY (Pearson r = 0.80).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	NMRK1 →	+0.728	+1.728	.003	<.001	3	3
OVARY	MMAB →	+1.880	+1.856	.002	<.001	3	3
CNS	TBC1D17 →	+0.974	+1.477	.001	<.001	3	3
LUNG_SCLC	CBFA2T2 →	+1.576	+1.397	.001	<.001	3	3
SKIN	IRF3 →	+0.933	+1.882	<.001	<.001	2	4
SKIN	CD151 →	+0.730	+1.654	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0009584 vs NMRK1 — KIDNEY

Explore this scatter interactively →