Short-term memory

Across TCGA patient cohorts, RNA activity of the Short-term memory pathway is significantly associated with the RNA expression of multiple genes, with the UCEC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are ZBTB39, SH3BGRL3, and B4GALT5, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Short-term memory activity versus ZBTB39 in UCEC (Pearson r = 0.28).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZBTB39 →	+0.544	+0.304	<.001	.004	3	4
OV	SH3BGRL3 →	-0.597	-0.149	.005	.002	3	3
HNSC	B4GALT5 →	+0.622	+0.458	.004	.008	3	3
COAD	PGLYRP4 →	-0.208	-0.235	.004	.003	3	2
COAD	TMC1 →	-0.104	-0.237	.003	.005	3	2
COAD	CCR9 →	-0.288	-0.201	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007614 vs ZBTB39 — UCEC

Explore this scatter interactively →