Short-term memory

Across TCGA cell cohorts, RNA activity of the Short-term memory pathway is significantly associated with the RNA expression of multiple genes, with the PANCREAS cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are AHCY, PHACTR2, and FBXW2, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Short-term memory activity versus AHCY in PANCREAS (Pearson r = -0.88).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	AHCY →	-1.363	-2.069	.006	<.001	3	2
PANCREAS	PHACTR2 →	-1.100	-1.749	.006	<.001	3	2
PANCREAS	FBXW2 →	-0.683	-1.515	.002	.003	3	2
PANCREAS	COPS5 →	-0.949	-2.069	.002	<.001	3	2
OVARY	CATSPERE →	+0.625	+1.935	.007	<.001	3	2
LUNG_NSCLC_LUAD	NDOR1 →	+1.089	+1.860	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007614 vs AHCY — PANCREAS

Explore this scatter interactively →