Golgi organization

Across TCGA patient cohorts, RNA activity of the Golgi organization pathway is significantly associated with the RNA expression of multiple genes, with the COAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LINC00937, SLC35E4, and KISS1R, each associated with the pathway in up to 2 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Golgi organization activity versus LINC00937 in COAD (Pearson r = 0.18).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC00937 →	+0.374	+0.438	.002	.007	3	2
COAD	SLC35E4 →	+1.252	+0.293	.004	.007	3	1
COAD	KISS1R →	+0.337	+0.484	.001	<.001	3	1
COAD	POLR1G →	+0.692	+0.320	<.001	.002	3	1
COAD	MOGAT1 →	+0.800	+0.305	.005	.004	3	1
COAD	GFPT2 →	+1.281	+0.320	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007030 vs LINC00937 — COAD

Explore this scatter interactively →