Potassium ion transport

Across TCGA cell cohorts, RNA activity of the Potassium ion transport pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LIPG, CNTROB, and ATP1A1, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Potassium ion transport activity versus LIPG in OVARY (Pearson r = 0.49).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	LIPG →	+2.436	+0.346	.003	.002	3	6
URINARY_TRACT	CNTROB →	-1.012	-0.311	.002	.007	3	5
PANCREAS	ATP1A1 →	+1.021	+0.367	.003	<.001	1	7
BONE	PLS1 →	+2.044	+0.171	.005	.002	3	5
BONE	GPAT3 →	+1.443	+0.208	.003	.004	3	5
URINARY_TRACT	ZNF771 →	-1.160	-0.305	.004	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0006813 vs LIPG — OVARY

Explore this scatter interactively →