Glycerol ether metabolic process

pathway activity — cross-omics
GO:0006662Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Glycerol ether metabolic process pathway is significantly associated with the protein abundance of multiple proteins, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are SEPTIN4, CRYL1, and SCIN, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSEPTIN4 →+0.623+0.056<.001<.00137
UCECCRYL1 →+0.453+0.054.002.00137
GBMSCIN →+0.664+0.041.007.00436
BRCASOD3 →+0.574+0.031<.001<.00136
BRCASYNPO2_S363 →+1.338+0.044<.001<.00136
BRCAGPD1 →+1.255+0.046<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration