Ovulation from ovarian follicle

Across TCGA cell cohorts, RNA activity of the Ovulation from ovarian follicle pathway is significantly associated with the RNA expression of multiple genes, with the LUNG_SCLC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are TCF24, PKD2L2, and RBCK1, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, TCF24 grouped by Ovulation from ovarian follicle-low versus -high activity in LUNG_SCLC.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	TCF24 →	-0.596	-0.766	.003	.002	3	3
SOFT_TISSUE	PKD2L2 →	-0.112	-0.927	.001	.007	3	3
BONE	RBCK1 →	-0.538	-1.047	.009	.005	3	3
BONE	RUSF1 →	-0.699	-1.488	.008	.002	3	3
BLOOD_Leukemia	PPP2CA →	-0.752	-1.003	.003	<.001	3	3
BLOOD_Leukemia	PYURF →	-0.530	-0.956	.008	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

TCF24 by Ovulation from ovarian follicle activity — LUNG_SCLC

Explore this box plot interactively →