Ribosomal small subunit export from nucleus

Across TCGA cell cohorts, RNA activity of the Ribosomal small subunit export from nucleus pathway is significantly associated with the RNA expression of multiple genes, with the SOFT_TISSUE cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CDK14, MBOAT2, and RANBP3, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Ribosomal small subunit export from nucleus activity versus CDK14 in SOFT_TISSUE (Pearson r = -0.54).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	CDK14 →	-3.277	-0.075	.003	.003	3	4
PANCREAS	MBOAT2 →	+0.969	+0.057	.002	.009	3	4
CNS	RANBP3 →	-0.419	-0.090	.001	<.001	3	4
BLOOD_Myeloma	GSTP1 →	-6.067	-0.130	.001	.003	3	3
SOFT_TISSUE	GNAI1 →	-3.301	-0.080	.005	.006	3	3
SOFT_TISSUE	SLAIN1 →	-1.400	-0.078	.009	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0000056 vs CDK14 — SOFT_TISSUE

Explore this scatter interactively →