ZXDA

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZXDA mutation is significantly associated with the RNA expression of many other genes, with 3,703 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZXDA-associated genes across cancer lineages are RNY1P8, OR2U1P, and MIR125B2. Each is linked with ZXDA in more than 2 cancer types. Because this analysis shows association rather than direction, both ZXDA-to-partner and partner-to-ZXDA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZXDA→partner) and Y-score (partner→ZXDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNY1P8 →+0.195+3.827<.001.00833
CESCOR2U1P →+0.045+4.020<.001.00932
CESCMIR125B2 →+0.950+3.997<.001.00132
SKCMSNORD114-12 →+0.367+7.816<.001.00832
LGGUSP9YP10 →+0.049+7.977<.001.00732
UCECSRCIN1 →-0.557-2.062<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,703 associations by consensus.

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