ZWINT

Across TCGA patient cohorts, ZWINT protein abundance is significantly associated with the RNA expression of many other genes, with 14,408 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZWINT-associated genes across cancer lineages are CENPI, RFC5, and NCAPH. Each is linked with ZWINT in more than 4 cancer types. Because this analysis shows association rather than direction, both ZWINT-to-partner and partner-to-ZWINT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZWINT versus CENPI in UCEC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZWINT→partner) and Y-score (partner→ZWINT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPI →	+1.007	+0.583	<.001	<.001	3	5
LSCC	RFC5 →	+0.557	+0.393	<.001	<.001	3	5
BRCA	NCAPH →	+1.028	+0.499	<.001	<.001	3	5
PDAC	E2F8 →	+1.226	+0.606	.002	<.001	3	5
LSCC	RFC4 →	+0.944	+0.567	<.001	<.001	3	5
BRCA	PLK1 →	+1.140	+0.567	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,408 associations by consensus.

ZWINT vs CENPI — UCEC

Explore this scatter interactively →