Across TCGA cell cohorts, ZSWIM9 mutation is significantly associated with the RNA expression of many other genes, with 777 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSWIM9-associated genes across cancer lineages are ASB17, SLC4A1, and DCAF12L1. Each is linked with ZSWIM9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSWIM9-to-partner and partner-to-ZSWIM9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSWIM9→partner) and Y-score (partner→ZSWIM9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.017	+4.807	<.001	.003	3	2
SKIN	SLC4A1 →	+0.296	+3.938	<.001	.005	3	1
BLOOD_Lymphoma	DCAF12L1 →	+0.012	+4.867	<.001	.009	3	1
BLOOD_Leukemia	ANKRD66 →	+0.241	+4.922	<.001	.009	3	1
LARGE_INTESTINE	PES1 →	+0.460	+2.800	.006	.001	3	1
LARGE_INTESTINE	ANKRD54 →	+0.479	+2.714	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 777 associations by consensus.

Exploration

ZSWIM9 survival (RNA) · tumor vs normal (RNA) · all ZSWIM9 data types