ZSWIM8-AS1

Across TCGA pan-cancer cohorts, ZSWIM8-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZSWIM8-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ZSWIM8-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZSWIM8-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCS show a favorable association.

BLCA, KIRC, and ACC are the cancer types where ZSWIM8-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	III,IV	0.533	0.341	<.001	101	view →
KIRC	DFS	Median	All	0.520	0.701	<.001	59	view →
ACC	DFS	Median	IV	0.127	0.559	<.001	42	view →
MESO	DFS	Tertile	IV	0.301	0.739	.013	36	view →
COAD	DFS	Quartile	All	0.432	0.714	.004	33	view →
UCS	DFS	Quartile	II,III,IV	0.619	0.243	.017	30	view →
PAAD	OS	Quartile	All	0.669	0.401	.007	27	view →
LUAD	DFS	Median	IV	0.306	0.764	.010	22	view →
PRAD	DFS	Tertile	All	0.814	0.924	<.001	20	view →
BRCA	OS	Median	All	0.974	0.950	.003	16	view →
STAD	OS	Quartile	II,III,IV	0.742	0.437	.014	11	view →
LGG	DFS	Quartile	All	0.331	0.460	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZSWIM8-AS1–BLCA (DFS)

Open the BLCA breakdown →