ZSWIM8-AS1

Across TCGA pan-cancer cohorts, ZSWIM8-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ZSWIM8-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ZSWIM8-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZSWIM8-AS1 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and KIRC are the cancer types where ZSWIM8-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZSWIM8-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.089	<.001	7	view →
BRCA	All	III,IV	−0.129	.002	6	view →
KIRC	Male	All	+0.048	<.001	6	view →
CHOL	All	All	+0.247	.010	2	view →
LIHC	All	All	+0.023	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ZSWIM8-AS1–KICH

Open the KICH breakdown →