Across TCGA patient cohorts, ZSCAN5B mutation is significantly associated with the RNA expression of many other genes, with 2,750 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN5B-associated genes across cancer lineages are CKAP2L, FCGRT, and KIF23. Each is linked with ZSCAN5B in more than 3 cancer types. Because this analysis shows association rather than direction, both ZSCAN5B-to-partner and partner-to-ZSCAN5B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN5B→partner) and Y-score (partner→ZSCAN5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CKAP2L →	+0.568	+1.788	.002	.001	3	4
SKCM	FCGRT →	-0.486	-2.473	.007	.001	3	3
UCEC	KIF23 →	+0.478	+1.534	.008	.005	3	3
UCEC	CEP55 →	+0.664	+3.000	.001	<.001	3	3
UCEC	BOLA3 →	+0.306	+2.711	.007	<.001	3	3
UCEC	GUF1 →	+0.625	+2.389	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,750 associations by consensus.

Exploration

ZSCAN5B survival (RNA) · tumor vs normal (RNA) · all ZSCAN5B data types