ZSCAN31

Across TCGA cell cohorts, ZSCAN31 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSCAN31-associated genes across cancer lineages are INSL5, ODF3, and C14orf180. Each is linked with ZSCAN31 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN31-to-partner and partner-to-ZSCAN31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSL5 grouped by ZSCAN31-low versus ZSCAN31-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN31→partner) and Y-score (partner→ZSCAN31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	INSL5 →	+0.401	+3.626	<.001	.006	3	1
LARGE_INTESTINE	ODF3 →	+0.058	+3.836	<.001	.003	3	1
LARGE_INTESTINE	C14orf180 →	+0.102	+3.155	.002	.008	3	1
LARGE_INTESTINE	PTH2R →	+1.077	+3.453	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

INSL5 by ZSCAN31 expression — LARGE_INTESTINE

Explore this box plot interactively →