ZSCAN29

Across TCGA pan-cancer cohorts, ZSCAN29 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ZSCAN29 data layer compared with 29 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZSCAN29 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated ZSCAN29 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

UCEC, STAD, and LIHC are the cancer types where ZSCAN29 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.972	0.607	.002	30	view →
STAD	OS	Median	All	0.195	0.588	.001	24	view →
LIHC	DFS	Median	All	0.079	0.553	.003	18	view →
LUAD	OS	Median	All	0.211	0.697	.005	12	view →
SKCM	DFS	Median	III,IV	0.036	0.613	<.001	12	view →
BLCA	DFS	Median	All	1.000	0.328	.033	4	view →
BRCA	OS	Median	All	0.239	0.580	.020	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

ZSCAN29–UCEC (DFS)

Open the UCEC breakdown →