Across TCGA patient cohorts, ZSCAN26 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN26-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and ERK2. Each is linked with ZSCAN26 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN26-to-partner and partner-to-ZSCAN26 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN26→partner) and Y-score (partner→ZSCAN26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.086	-2.301	.044	.034	3	1
UCEC	EGFR_pY1068 →	-0.271	-2.321	.010	.034	3	1
UCEC	ERK2 →	+0.203	+2.584	.012	.010	3	1
UCEC	ACC1 →	+0.323	+2.321	.036	.034	3	1
UCEC	HSP70 →	-0.400	-1.700	.019	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.165	-2.999	.021	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZSCAN26 survival (RNA) · tumor vs normal (RNA) · all ZSCAN26 data types