Across TCGA cell cohorts, ZSCAN25 mutation is significantly associated with the mutation status of many other genes, with 6,161 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSCAN25-associated genes across cancer lineages are SIN3A, PTPN23, and GRIA4. Each is linked with ZSCAN25 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZSCAN25-to-partner and partner-to-ZSCAN25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN25→partner) and Y-score (partner→ZSCAN25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SIN3A →	+4.807	+4.807	.008	.008	1	4
LUNG_NSCLC_LUAD	PTPN23 →	+5.339	+4.772	.004	.004	1	3
BLOOD_Leukemia	GRIA4 →	+3.662	+3.523	<.001	<.001	1	3
BLOOD_Leukemia	GAREM2 →	+4.662	+3.963	<.001	<.001	1	3
LARGE_INTESTINE	AGAP1 →	+2.874	+3.632	.002	.002	1	3
BLOOD_Leukemia	NRG2 →	+4.247	+3.560	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,161 associations by consensus.

Exploration

ZSCAN25 survival (RNA) · tumor vs normal (RNA) · all ZSCAN25 data types