ZSCAN20

Across TCGA cell cohorts, ZSCAN20 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible ZSCAN20-associated genes across cancer lineages are MYMK, USP17L18, and LYZL1. Each is linked with ZSCAN20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN20-to-partner and partner-to-ZSCAN20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYMK grouped by ZSCAN20-low versus ZSCAN20-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN20→partner) and Y-score (partner→ZSCAN20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MYMK →	+0.014	+4.029	<.001	.007	3	1
PANCREAS	USP17L18 →	+0.005	+3.786	<.001	.004	3	1
LUNG_NSCLC_LUSC	LYZL1 →	+0.026	+4.643	<.001	.008	3	1
LUNG_NSCLC_LUSC	CCL18 →	+0.040	+4.643	<.001	.008	3	1
URINARY_TRACT	UNCX →	+0.010	+4.087	<.001	.009	3	1
BLOOD_Lymphoma	OR1N2 →	+0.014	+3.342	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MYMK by ZSCAN20 expression — PANCREAS

Explore this box plot interactively →