ZSCAN2

Across TCGA patient cohorts, ZSCAN2 mutation is significantly associated with the RNA expression of many other genes, with 3,522 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN2-associated genes across cancer lineages are SLBP, GFM2, and METTL17. Each is linked with ZSCAN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZSCAN2-to-partner and partner-to-ZSCAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLBP grouped by ZSCAN2-low versus ZSCAN2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN2→partner) and Y-score (partner→ZSCAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLBP →	+0.473	+2.678	.002	<.001	3	3
UCEC	GFM2 →	+0.648	+2.263	<.001	<.001	3	3
UCEC	METTL17 →	+0.307	+3.818	.004	<.001	3	3
UCEC	SNUPN →	+0.387	+2.828	.001	.001	3	3
UCEC	PSMA4 →	+0.432	+2.295	<.001	<.001	3	3
COAD	JKAMP →	+0.481	+3.372	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,522 associations by consensus.

SLBP by ZSCAN2 expression — UCEC

Explore this box plot interactively →