ZSCAN2

Across TCGA cell cohorts, ZSCAN2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSCAN2-associated genes across cancer lineages are OR51D1, OR6Q1, and MYH13. Each is linked with ZSCAN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN2-to-partner and partner-to-ZSCAN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51D1 grouped by ZSCAN2-low versus ZSCAN2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN2→partner) and Y-score (partner→ZSCAN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR51D1 →	+0.013	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR6Q1 →	+0.018	+4.437	<.001	.004	3	1
LARGE_INTESTINE	MYH13 →	+0.636	+4.054	<.001	.004	3	1
BLOOD_Lymphoma	S100G →	+0.054	+4.867	.001	.009	3	1
SKIN	WNT9B →	+0.046	+4.467	<.001	.004	3	1
SKIN	CYP4F8 →	+0.031	+5.217	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR51D1 by ZSCAN2 expression — LARGE_INTESTINE

Explore this box plot interactively →