ZSCAN18

Across TCGA cell cohorts, ZSCAN18 mutation is significantly associated with the RNA expression of many other genes, with 358 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSCAN18-associated genes across cancer lineages are OR10V1, OR7E24, and KRTAP5-4. Each is linked with ZSCAN18 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN18-to-partner and partner-to-ZSCAN18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by ZSCAN18-low versus ZSCAN18-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN18→partner) and Y-score (partner→ZSCAN18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR10V1 →	+0.032	+4.369	<.001	.008	3	2
SOFT_TISSUE	OR7E24 →	+0.022	+4.369	<.001	.008	3	1
SOFT_TISSUE	KRTAP5-4 →	+0.024	+4.369	<.001	.008	3	1
LUNG_NSCLC_LUSC	DEFB124 →	+0.163	+4.108	<.001	.005	3	1
URINARY_TRACT	C16orf90 →	+0.023	+5.087	<.001	.004	3	1
PANCREAS	SHISAL2B →	+0.172	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 358 associations by consensus.

OR10V1 by ZSCAN18 expression — SOFT_TISSUE

Explore this box plot interactively →