ZSCAN10

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZSCAN10 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZSCAN10 data layer compared with 20 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZSCAN10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZSCAN10 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC and HNSC are the cancer types where ZSCAN10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianIII,IV1.0000.256.00252view →
HNSCDFSQuartileAll0.8370.414.0136view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ZSCAN10–UCEC (DFS)

Kaplan–Meier survival curve for ZSCAN10 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration