ZSCAN10

Across TCGA pan-cancer cohorts, ZSCAN10 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of ZSCAN10’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZSCAN10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZSCAN10 is over-expressed in tumor.

HNSC, LIHC, and KIRP are the cancer types where ZSCAN10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZSCAN10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	IV	+0.035	<.001	8	view →
LIHC	All	All	+0.026	.002	6	view →
KIRP	All	III,IV	+0.034	.036	2	view →
STAD	Male	III,IV	+0.065	.011	1	view →
CHOL	All	All	+0.051	.008	1	view →
KIRC	Male	IV	+0.023	.048	1	view →
COAD	All	All	+0.017	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

ZSCAN10–HNSC

Open the HNSC breakdown →