ZSCAN10

Across TCGA patient cohorts, ZSCAN10 mutation is significantly associated with the RNA expression of many other genes, with 4,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZSCAN10-associated genes across cancer lineages are ABALON, CHEK1, and DLAT. Each is linked with ZSCAN10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZSCAN10-to-partner and partner-to-ZSCAN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABALON grouped by ZSCAN10-low versus ZSCAN10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN10→partner) and Y-score (partner→ZSCAN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABALON →	+0.389	+2.212	.001	.001	3	3
UCEC	CHEK1 →	+0.626	+1.914	<.001	<.001	3	3
UCEC	DLAT →	+0.624	+2.857	<.001	<.001	3	3
UCEC	AP1S3 →	+0.378	+1.697	.008	.001	3	3
UCEC	NUS1 →	+0.460	+2.191	<.001	<.001	3	3
UCEC	PPP2R5E →	+0.462	+3.721	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,258 associations by consensus.

ABALON by ZSCAN10 expression — UCEC

Explore this box plot interactively →