ZSCAN10

Across TCGA cell cohorts, ZSCAN10 mutation is significantly associated with the RNA expression of many other genes, with 875 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZSCAN10-associated genes across cancer lineages are OR9G1, C12orf57, and MSTN. Each is linked with ZSCAN10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZSCAN10-to-partner and partner-to-ZSCAN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9G1 grouped by ZSCAN10-low versus ZSCAN10-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZSCAN10→partner) and Y-score (partner→ZSCAN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR9G1 →	+0.030	+5.087	<.001	.004	3	2
BLOOD_Leukemia	C12orf57 →	+0.939	+3.489	.006	.001	3	2
BLOOD_Leukemia	MSTN →	+0.299	+2.798	<.001	.003	3	2
BLOOD_Leukemia	ZNF18 →	+0.661	+3.228	<.001	.004	3	2
BLOOD_Leukemia	EDA →	+0.728	+3.470	.001	.004	3	2
BLOOD_Leukemia	SNTG2 →	+0.933	+2.584	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 875 associations by consensus.

OR9G1 by ZSCAN10 expression — URINARY_TRACT

Explore this box plot interactively →